Master Thesis Internship

- Master Thesis Internship: Econometrics & Health Data Modelingtrics Compare modeling approaches and discover how a screening program against gastric cancer can be cost effective. Build a Taiwanese version of an Erasmus MC microsimulation model and shape healthcare policy as a full member of our research team. - Closing date 31-12-2026 - 3430 - 36 hours - Research university - Internships - Closing date 31-12-2026 - 3430 Job description Approximately half of the Asian population is infected with H. pylori. Although most infections remain asymptomatic, H. pylori can lead to gastric cancer. To reduce the burden of gastric cancer, Taiwan recently introduced a screening program in which individuals are tested and treated if positive. Previously, the cost-effectiveness of this programme was only evaluated using simplified Markov simulation models. The goal of this master thesis project is to compare different modelling approaches for evaluating the cost-effectiveness of H. pylori screen-and-treat in Taiwan. You will develop and apply a Taiwanese version of MISCAN-gastric, a microsimulation model developed at Erasmus MC, calibrating the model to local data using genetic algorithms or alternative calibration methods. You will compare the predictions to those of previously published models, focusing on health outcomes and cost-effectiveness An important focus will be to understand why the models produce similar or different outcomes. This includes investigating the influence of differences in model structure and parameters, assumptions in the statistical distributions of precursor disease and the timing of treatment effects. Ultimately, the project aims to assess the extent to which cost-effectiveness conclusions depend on the modelling approach and what this means for healthcare policy in Taiwan. Depending on your interest and progress, there is considerable scope to explore additional methodological or epidemiological questions, ...

-硕士论文实习：计量经济学与健康数据建模 比较建模方法，探索胃癌筛查项目如何实现成本效益。构建Erasmus MC微观模拟模型的台湾版本，并作为我们研究团队的正式成员塑造医疗政策。-截止日期2026年12月31日-3430-36小时-研究型大学-实习-截止日期2026年12月31日-3430 职位描述 大约一半的亚洲人口感染幽门螺杆菌。尽管大多数感染保持无症状，幽门螺杆菌可导致胃癌。为减轻胃癌负担，台湾最近引入了一项筛查项目，对个体进行检测并在阳性时给予治疗。此前，该项目的成本效益仅通过简化的Markov模拟模型进行评估。本硕士论文项目的目标是比较不同建模方法在评估台湾幽门螺杆菌筛查-治疗成本效益方面的表现。你将开发并应用MISCAN-gastric的台湾版本，这是一个在Erasmus MC开发的微观模拟模型，使用遗传算法或替代校准方法将模型校准至本地数据。你将把预测结果与先前发表的模型进行比较，重点关注健康结局和成本效益。一个重要关注点是理解模型为何产生相似或不同的结果。这包括研究模型结构和参数差异、前驱疾病统计分布假设以及治疗效应时机的影响。最终，该项目旨在评估成本效益结论在多大程度上取决于建模方法，以及这对台湾医疗政策意味着什么。根据你的兴趣和进展，有相当大的空间探索额外的方法学或流行病学问题，...

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